• NikiBifidobacterium Longum ?
Bifidobacterium longum yamye ifite umwanya wingenzi mubushakashatsi bwikiremwamuntu ku isano iri hagati ya mikorobe nubuzima. Nk’umunyamuryango mwinshi kandi ukoreshwa cyane mu bwoko bwa Bifidobacterium, ubunini bw’isoko ku isi biteganijwe ko burenga miliyari 4.8 z’amadolari y’Amerika mu 2025, hamwe n’ubwiyongere bw’umwaka buri mwaka bwa 11.3%. Ubushakashatsi bwakozwe mu 2025 bwasohotse muri Nature Microbiology bwemeje ko uburebure bwa Bifidobacterium bushobora kugenga imyitwarire y’amaganya binyuze mu nda y’ubwonko, byerekana ko uyu “kavukire amara” arimo ahindura imiterere y’inganda z’ubuzima mu rwego rushya.
Uburebure bwa Bifidobacterium: Gram-positif, idakora spore, na anaerobic rwose, ikura neza kuri 36-38 ° C kandi yihanganira pH ya 5.5-7.5. Ubucucike bwa selile bukomeye mumico ya MRS burashobora kugera kuri 10 ^ 10 CFU / mL.
Gutegura inganda: Ukoresheje tekinoroji ya microencapsulation, igipimo cyiza cyo kubaho kwingirabuzimafatizo cyiyongereye kugera kuri 92%.
• Ni izihe nyunguBifidobacterium Longum?
Ukurikije ubushakashatsi burenga 3.000 kwisi yose, Bifidobacterium longum yerekana ingaruka zibinyabuzima zitandukanye:
1. Gucunga neza ubuzima
Microbiome Modulation: Irwanya indwara ziterwa na peptide ya mikorobe (nka bifidocine), ikongera ubwinshi bwa bifidobacteria yo munda inshuro 3-5.
Gusana Mucosal: Igenzura imvugo ya poroteyine ya occludin, igabanya ubwonko bwo munda (FITC-dextran permeability yagabanutseho 41%), kandi igabanya syndrome de munda.
2. Amabwiriza agenga ubudahangarwa
Indinganizo ya Cytokine:Uburebure bwa Bifidobacteriumitera ururenda rwa IL-10 (yongerera imbaraga inshuro 2,1), ikabuza TNF-α (igabanukaho 58%), kandi igatera indwara zifata umura.
Kwivanga kwa Allergie: Igabanya serumu IgE ku kigero cya 37% kandi igabanya indwara ya dermatite ya Atopic ku bana bato (OR = 0.42).
3. Guhindura imitekerereze ya Neuropsychiatric
Ingaruka ya Gut-Ubwonko Axis: Ikora inzira yinzira ya vagus, igabanya igihe cyo koga ku gahato ku mbeba zijyanye no guhangayika ku kigero cya 53%. Interabolic Intervention: SCFAs (acide-fatty acide acide) igenga reseptor ya GABA kandi ikanoza ibitotsi byimbeba zerekana imihangayiko idakira.
4. Kurinda indwara no kuvura
Indwara ya Metabolic: Kugabanya glucose yamaraso yo kwiyirizaho 1,8 mmol / L ku barwayi barwaye diyabete yo mu bwoko bwa 2 kandi byazamuye igipimo cya HOMA-IR 42%.
Ubuvuzi bwa Kanseri ya Adjuvant: Kwivanga na 5-FU byongereye ubuzima bwo kubaho kw'imbeba zifite kanseri y'amara ku kigero cya 31% kandi zigabanya ibibyimba 54%.
Ni ubuhe buryo bukoreshwaBifidobacterium Longum ?
Uburebure bwa Bifidobacterium burimo kurenga imipaka gakondo, bugizwe nibice bitandatu byingenzi bikoreshwa:
Inganda zikora ibiribwa
Ibikomoka ku mata bisembuye: Iyo bihujwe na Streptococcus thermophilus, byongera ubwiza bwa yogurt inshuro 2,3 kandi bikongerera igihe cyo kubaho iminsi 45.
Ibiryo bikora: Ongeraho 5 × 10 ^ 9 CFU / g mu tubari tw’ibinyampeke byongera amara inshuro kuva kuri 2,1 kugeza kuri 4.3 mu cyumweru mu bantu bafite impatwe.
2. Imiti
Kurenza ibiyobyabwenge (OTC):Uburebure bwa Bifidobacteriuminyabutatu nzima ya capsules (Lizhu Changle) igurishwa buri mwaka irenga agasanduku ka miliyoni 230 kandi bifite akamaro 89% mukuvura impiswi.
Ibinyabuzima: Ibinini byihuta byihuta byongera umuvuduko wa colonike inshuro eshatu kandi byemerewe na FDA yihuta.
3. Ubuhinzi n'ibiryo
Ubworozi n'ubworozi bw'inkoko: Ongeramo 1 × 10 ^ 8 CFU / kg y'ibiryo bigabanya impiswi mu ngurube 67% kandi byongera ihinduka ryibiryo 15%. Kurinda Ibimera: Gutera Rhizosiporo byagabanije bagiteri yinyanya ziyongera kuri 42% kandi umusaruro wiyongereyeho 18%.
4. Ibikoresho byo kwisiga
Gusana inzitizi: 0.1% ivamo bagiteri yagabanije uruhu TEWL (gutakaza amazi ya transepidermal) ku kigero cya 38%, ibona icyemezo cya EU ECOCERT.
Kurwanya Gusaza Porogaramu: Byahujwebifidobacterium longumhamwe na peptide, byagabanije ubujyakuzimu bw’iminkanyari ya periorbital ku kigero cya 29%, ibona impamyabumenyi yihariye yo kwisiga yatanzwe na Minisiteri y’ubuzima y’Ubuyapani, umurimo n’imibereho myiza.
5. Ikoranabuhanga mu bidukikije
Gutunganya amazi mabi: Amoniya ya azote yangirika ya 78% yagezweho, bigabanya umusaruro wibyondo 35%.
Ibikomoka kuri peteroli: Umusemburo wa aside ya asike wiyongereye kugera kuri 12.3 g / L, ugabanya ibiciro 40% ugereranije nibikorwa gakondo.
6. Ubuzima bwamatungo
Ibiryo by'amatungo: Ongeramo 2 × 10 ^ 8 CFU / kg kubiryo byimbwa byazamuye amanota ya fecal 61% kandi bigabanya impiswi.
Guhindura imyitwarire: spray yagabanije guhangayikishwa no gutandukana kandi igabanya imyitwarire ikaze 54%.
• Icyatsi gishya gitanga ubuziranengeBifidobacterium LongumIfu
Igihe cyo kohereza: Nyakanga-29-2025
