● Kodi?Thiamine Hydrochloride ?
Thiamine hydrochloride ndi mtundu wa hydrochloride wa vitamini B₁, wokhala ndi formula yamankhwala C₁₂H₁₇ClN₄OS·HCl, molecular weight 337.27, ndi CAS nambala 67-03-8. Ndi ufa wonyezimira wonyezimira wonyezimira wonyezimira wokhala ndi fungo losamveka bwino la chinangwa cha mpunga ndi kukoma kowawa. Ndikosavuta kuyamwa chinyezi mukamauma (imatha kuyamwa chinyezi cha 4% ikakhala ndi mpweya). Zofunika kwambiri zakuthupi ndi zamankhwala zimaphatikizapo:
Kusungunuka:Amasungunuka kwambiri m'madzi (1g/mL), amasungunuka pang'ono mu ethanol ndi glycerol, komanso osasungunuka mu zosungunulira za organic monga ether ndi benzene.
Kukhazikika:Chokhazikika m'malo a acidic (pH 2-4) ndipo chimatha kupirira kutentha kwa 140 ° C; koma amawola mofulumira mu njira zopanda ndale kapena zamchere ndipo amazimitsa mosavuta ndi kuwala kwa ultraviolet kapena redox agents.
Makhalidwe ozindikira:Imakhudzidwa ndi ferric cyanide kupanga chinthu cha fulorosenti ya buluu "thiochrome", yomwe imakhala maziko a kusanthula kachulukidwe38.
Njira yokonzekera kwambiri padziko lonse lapansi ndi kaphatikizidwe ka mankhwala, omwe amagwiritsa ntchito acrylonitrile kapena β-ethoxyethyl propionate monga zopangira ndipo amapangidwa kudzera mu condensation, cyclization, m'malo ndi masitepe ena, ndi chiyero choposa 99%.
●Kodi Ubwino Wake Ndi ChiyaniThiamine Hydrochloride ?
Thiamine hydrochloride imasinthidwa kukhala mawonekedwe a thiamine pyrophosphate (TPP) m'thupi la munthu, ndipo imagwira ntchito zingapo zakuthupi:
1. Mphamvu ya metabolism core:monga coenzyme ya α-ketoacid decarboxylase, imatenga nawo gawo mwachindunji pakusintha kwa glucose kukhala ATP. Zikasoweka, zimayambitsa kudzikundikira kwa pyruvate, zomwe zimayambitsa lactic acidosis ndi vuto lamphamvu.
2. Chitetezo cha manjenje:Kusunga yachibadwa conduction wa mitsempha zikhumbo. Kuperewera kwakukulu kumayambitsa beriberi, zomwe zimakhala ndi zizindikiro monga peripheral neuritis, muscular atrophy, ndi kulephera kwa mtima. M'mbiri yakale, zachititsa mliri waukulu ku Asia, kupha anthu masauzande ambiri pachaka.
3. Mtengo wa kafukufuku womwe ukubwera:
Chitetezo cha myocardial:Kukhazikika kwa 10μM kumatha kusokoneza kuwonongeka kwa cell ya acetaldehyde-induced myocardial, kuletsa caspase-3 activation, ndikuchepetsa mapangidwe a protein carbonyl.
Anti-neurodegeneration:Poyesa nyama, kuperewera kungayambitse kudzikundikira kwachilendo kwa mapuloteni a β-amyloid muubongo, omwe amagwirizana ndi matenda a Alzheimer's.
Magulu omwe ali pachiwopsezo chachikulu chosowa ndi awa:kumwa kwanthawi yayitali mpunga woyera woyengedwa ndi ufa, zidakwa (ethanol imalepheretsa kuyamwa kwa thiamine), amayi apakati, ndi odwala omwe akutsekula m'mimba kosatha.
●Kodi Kugwiritsa Ntchito Ndi ChiyaniThiamine Hydrochloride ?
1. Makampani azakudya (gawo lalikulu kwambiri):
Zakudya zowonjezera:kuwonjezeredwa ku phala (3-5mg/kg), chakudya cha makanda (4-8mg/kg), ndi zakumwa zamkaka (1-2mg/kg) kuti zithandizire kutayika kwa michere yomwe imabwera chifukwa cha kukonza bwino.
Zovuta zaukadaulo:Chifukwa ndikosavuta kuwola m'malo amchere, zotumphukira monga thiamine nitrate zimagwiritsidwa ntchito m'malo mwazakudya zophikidwa.
2. Ntchito zachipatala:
Zochizira:jakisoni amagwiritsidwa ntchito pochiza mwadzidzidzi beriberi (neurological/heart failure), ndipo kukonzekera pakamwa kumagwiritsidwa ntchito ngati chithandizo chothandizira cha neuritis ndi indigestion.
Combination therapy:kuphatikizidwa ndi othandizira a magnesium kuti apititse patsogolo mphamvu ya Wernicke encephalopathy ndikuchepetsa kubwereza.
3. Agriculture ndi Biotechnology:
Zolimbikitsa zolimbana ndi matenda:Chithandizo cha 50mM cha mpunga, nkhaka, ndi zina zotero, chimayambitsa majini okhudzana ndi tizilombo toyambitsa matenda (PR majini), ndikuwonjezera kukana kwa bowa ndi mavairasi.
Zakudya zowonjezera:Sinthani mphamvu ya metabolism ya shuga mu ziweto ndi nkhuku, makamaka m'malo opanikizika ndi kutentha (kuchuluka kwa kufunikira kwa kutuluka thukuta).
● NEWGREEN Supply High QualityThiamine HydrochlorideUfa
Nthawi yotumiza: Jun-30-2025
