• Kodi N'chiyani?Lycopene ?
Lycopene ndi carotenoid yachilengedwe, yomwe imapezeka mu zipatso ndi ndiwo zamasamba monga tomato. Kapangidwe kake ka mankhwala kumakhala ndi ma 11 conjugated ma bond awiri ndi ma 2 osalumikizana pawiri, ndipo ali ndi ntchito yolimba ya antioxidant.
Lycopene imatha kuteteza umuna ku ROS, potero kumapangitsa kuti umuna ukhale wabwino, kuletsa prostate hyperplasia, khansa ya prostate cell carcinogenesis, kuchepetsa kuchuluka kwa chiwindi chamafuta, atherosulinosis ndi matenda amtima, kukonza chitetezo chamunthu, ndikuchepetsa kuwonongeka kwa khungu chifukwa cha kuwala kwa ultraviolet.
Thupi la munthu silingathe kupanga lycopene palokha, ndipo limatha kulowetsedwa kudzera mu chakudya. Pambuyo mayamwidwe, izo makamaka kusungidwa mu chiwindi. Zitha kuwoneka mu plasma, seminal vesicles, prostate ndi minofu ina.
• Ubwino Wake Ndi Chiyani?LycopeneKwa Kukonzekera Kwa Mimba Yamamuna?
Pambuyo pa RAGE activation, imatha kuyambitsa ma cell ndikupangitsa kupanga ROS, potero kumakhudza ntchito ya umuna. Monga antioxidant wamphamvu, lycopene imatha kuzimitsa mpweya wa singlet, kuchotsa ROS, ndikuletsa ma lipoprotein a umuna ndi DNA kukhala oxidized. Kafukufuku wawonetsa kuti lycopene imatha kuchepetsa kuchuluka kwa cholandilira cha advanced glycation end products (RAGE) mu umuna wamunthu, potero kumapangitsa kuyenda kwa umuna.
Mankhwala a Lycopene ali ndi machende ambiri a amuna athanzi, koma otsika mwa amuna osabereka. Kafukufuku wazachipatala apeza kuti lycopene imatha kupititsa patsogolo umuna wa amuna. Amuna osabereka azaka zapakati pa 23 mpaka 45 adafunsidwa kuti amwe lycopene pakamwa kawiri pa tsiku. Miyezi isanu ndi umodzi pambuyo pake, ndende ya umuna, ntchito ndi mawonekedwe awo adayang'aniridwanso. Amuna atatu mwa magawo atatu aliwonse anali atasintha kwambiri kuyenda kwa umuna ndi morphology, ndipo umuna umakhala wabwino kwambiri.
• Ubwino Wake Ndi Chiyani?LycopeneKwa Male Prostate?
1. Prostatic Hyperplasia
Prostatic hyperplasia ndi matenda ofala mwa amuna, ndipo m'zaka zaposachedwa, chiwerengero cha anthu chikuchepa kwambiri. Zizindikiro zotsika za mkodzo (kuthamanga kwa mkodzo / kukodza pafupipafupi / kusakwanira) ndizizindikiro zazikulu zachipatala, zomwe zimakhudza kwambiri moyo wa odwala.
Lycopeneimatha kuletsa kuchuluka kwa ma cell a prostate epithelial, kulimbikitsa apoptosis mu minofu ya prostate, kulimbikitsa kulumikizana kwa intercellular gap mphambano kuti ateteze kugawikana kwa maselo, komanso kuchepetsa mogwira mtima kuchuluka kwa zinthu zotupa monga interleukin IL-1, IL-6, IL-8 ndi chotupa necrosis factor (TNF-α) kuti agwiritse ntchito zotsutsana ndi zotupa.
Mayesero azachipatala apeza kuti lycopene imatha kusintha prostate hyperplasia komanso mawonekedwe osalala a minofu ya chikhodzodzo mwa anthu onenepa ndikuchepetsa zizindikiro za mkodzo wam'munsi mwa amuna. Lycopene ili ndi chithandizo chabwino komanso chowongolera pazizindikiro zam'munsi zamkodzo za amuna zomwe zimayambitsidwa ndi prostate hypertrophy ndi hyperplasia, zomwe zimagwirizana ndi antioxidant wamphamvu komanso anti-yotupa zotsatira za lycopene.
2. Khansa ya Prostate
Pali mabuku ambiri azachipatala ochirikiza zimenezolycopenemuzakudya za tsiku ndi tsiku zimathandizira kwambiri popewa khansa ya prostate, ndipo kumwa lycopene kumayenderana moyipa ndi chiopsezo cha khansa ya prostate. Njira yake imakhulupirira kuti ikugwirizana ndi kukhudza mawonekedwe a majini ndi mapuloteni okhudzana ndi chotupa, kuletsa kuchulukana kwa maselo a khansa ndi kumamatira, komanso kulimbikitsa kulumikizana kwapakati.
Kuyesa zotsatira za lycopene pa kuchuluka kwa kupulumuka kwa maselo a khansa ya prostate: M'mayesero azachipatala, lycopene idagwiritsidwa ntchito pochiza ma cell a khansa ya prostate DU-145 ndi LNCaP.
Zotsatira zinasonyeza zimenezolycopenechinali ndi cholepheretsa chachikulu pakuchulukira kwa maselo a DU-145, ndipo zolepheretsa zidawoneka pa 8μmol/L. Zotsatira zoletsa za lycopene pa izo zinali zogwirizana ndi mlingo, ndipo chiwerengero chapamwamba choletsa chikhoza kufika 78%. Panthawi imodzimodziyo, ikhoza kulepheretsa kwambiri kuchulukira kwa LNCaP, ndipo pali chiyanjano chodziwikiratu cha zotsatira za mlingo. Pazipita zopinga mlingo pa mlingo wa 40μmol/L akhoza kufika 90%.
Zotsatira zikuwonetsa kuti lycopene imatha kuletsa kuchuluka kwa maselo a prostate ndikuchepetsa chiopsezo cha khansa ya prostate kukhala khansa.
Nthawi yotumiza: Nov-20-2024
