Glutathione: Antioxidant Yamphamvu

●Ndi chiyaniGlutathione ?

Glutathione (GSH) ndi gulu la tripeptide (mamolekyulu a C₁₀H₁₇N₃O₆S) opangidwa ndi glutamic acid, cysteinepandi glycine olumikizidwa ndiγ- amide zomangira. Pakatikati pake ndi gulu la sulfhydryl (-SH) pa cysteine, lomwe limapatsa mphamvu yochepetsera.

Mitundu iwiri ikuluikulu ya thupi ya glutathione:

1. Kuchepetsa glutathione (GSH): amawerengera zoposa 90% ya kuchuluka kwa thupi lonse ndipo ndi njira yaikulu ya antioxidant ndi detoxification ntchito; amachotsa mwachindunji ma free radicals ndikuteteza maselo ku kuwonongeka kwa okosijeni.

2. Oxidized glutathione (GSSG): yopangidwa ndi makutidwe ndi okosijeni a mamolekyu awiri a GSH (GSSG), ndi ntchito yofooka ya thupi; pansi pa catalysis ya glutathione reductase, zimatengera NADPH kuti itsitsidwe kukhala GSH kuti isunge ma cell redox balance.

●Kodi Ubwino Wawo Ndi ChiyaniGlutathione ?

1. Ntchito Zazikulu Zathupi

Detoxification ndi chitetezo cha chiwindi:

Glutathione akhoza chelate heavy metal ( lead, mercury ), poizoni wa mankhwala (monga cisplatin) ndi metabolites ya mowa. Jekeseni wa mtsempha wa 1800mg/tsiku ukhoza kupititsa patsogolo ntchito ya chiwindi, ndipo mphamvu yochizira matenda a chiwindi chauchidakwa ndi yoposa 85%.

Chithandizo chothandizira anti-chotupa:

Glutathione akhoza rchepetsani chemotherapy nephrotoxicity, onjezerani zochita za maselo achilengedwe (NK cell) ndi 2 times, ndikuletsa chotupa cell oxidative kupsinjika.

Chitetezo cha Mitsempha ndi Ophthalmic:

Glutathione akhoza rkuchepetsa zizindikiro zoyambirira za matenda a Parkinson ndi kuchepetsa dopamine neurotoxicity; kugwiritsa ntchito madontho a m'maso kumatha kukonza zilonda zam'maso ndikulepheretsa kukula kwa ng'ala.

2. Ntchito Zaumoyo ndi Kukongola

Kuletsa kukalamba kwa chitetezo chamthupi: Yambitsani mapuloteni a Sirtuins ndikuchedwetsa kufupikitsa kwa telomere; kuonjezera ntchito ya lymphocyte ndi kuchepetsa kutulutsidwa kwa zinthu zotupa;

Kuyera ndi kuchotsa mawanga: Kuletsa ntchito ya tyrosinase ndikuchepetsa kupanga melanin. Zatsimikiziridwa kuti zimathandizira kuti khungu likhale lolimba komanso kuchepetsa kuya kwa makwinya ndi 40%.

●Kodi Kugwiritsa Ntchito Ndi ChiyanisZa Glutathione ?

1. Medical Field

Jekeseni: amagwiritsidwa ntchito poteteza mankhwala amphamvu (1.5g/m² mlingo), thandizo loyamba la poizoni, ndipo amafunika kusungidwa kutali ndi kuwala;

Kukonzekera pakamwa: kugwiritsa ntchito nthawi yayitali (200-500mg / nthawi, miyezi yoposa 6) kuonjezera nkhokwe za thupi la GSH ndikuthandizira kuchiza matenda aakulu a chiwindi.

2. Chakudya Chogwira Ntchito

Antioxidant zowonjezera: pawiri vitamini C (500mg vitamini C tsiku akhoza kuonjezera mlingo wa GSH ndi 47%) kapena selenium kuonjezera chitetezo chokwanira;

Chakudya choteteza chiwindi ndi chiwindi: chowonjezeraglutathionezakumwa zogwira ntchito kuti zipititse patsogolo kagayidwe ka mowa ndikuchepetsa kuwonongeka kwa chiwindi.

3. Cosmetic Innovation

Whitening essence: amagwiritsidwa ntchito kwambiri pamsika waku Asia kuti aletse melanin, kuphatikiza ukadaulo wa microneedle kuti upititse patsogolo kulowa kwa khungu;

Njira yoletsa kukalamba: liposome encapsulated GSH imakana kuwonongeka kwa ultraviolet ndipo imachepetsa photoaging erythema ndi 31% -46%.

4. Kugwiritsa Ntchito Ma Emerging Technologies

Kutumiza mankhwala omwe akuyembekezeredwa: Ma nanogel omvera GSH amatha kutulutsa mankhwala a chemotherapy (monga doxorubicin) pamalo otupa, kuwongolera magwiridwe antchito ndikuchepetsa zotsatira zoyipa;

Kuteteza chilengedwe ndi ulimi: Pangani zinthu zomwe sizingawonongeke ndikuwunika zowonjezera zakudya kuti muteteze chitetezo cha ziweto ndi nkhuku.

Kuchokera pa patent yochotsa yisiti mpaka kupanga matani masauzande ambiri mu biology yopanga masiku ano, njira yopangira mafakitale ya glutathione yatsimikizira kusinthika kwa "cell guardian" kukhala "injini yaukadaulo". M'tsogolomu, pomaliza kutsimikizira kwachipatala kwa zizindikiro zatsopano za neuroprotection ndi anti-kukalamba, molekyulu ya antioxidant iyi yonyamula moyo idzapitiriza kupereka mphamvu ya sayansi pa thanzi laumunthu ndi moyo wautali. 

●Zatsopano ZatsopanoGlutathione Ufa