●Ndi chiyani Caffeic Acid?
Caffeic acid, dzina la mankhwala 3,4-dihydroxycinnamic acid (molecular formula C₉H₈O₄, CAS No. 331-39-5), ndi chilengedwe cha phenolic acid chomwe chimapezeka kwambiri mu zomera. Ndi mawonekedwe achikasu a kristalo, amasungunuka pang'ono m'madzi ozizira, amasungunuka mosavuta m'madzi otentha, ethanol ndi ethyl acetate, ndi malo osungunuka a 194-213 ℃ (njira zosiyanasiyana zimasiyanasiyana), lalanje-wofiira mu njira ya alkaline, ndi mdima wobiriwira pokhudzana ndi ferric chloride.
Zoyambira zoyambira zikuphatikizapo:
●Zomera zamankhwala:Asteraceae Solidago, sinamoni, dandelion (yokhala ndi caffeic acid ≥ 0.02%), Ranunculaceae Cimicifuga rhizome;
●Zipatso ndi ndiwo zamasamba:mandimu peel, mabulosi abulu, apulo, broccoli ndi masamba a cruciferous;
●Zosakaniza zakumwa:nyemba za khofi (mu mawonekedwe a chlorogenic acid esters), vinyo (wophatikizidwa ndi tartaric acid).
Ukadaulo wamakono umagwiritsa ntchito ukadaulo wapamwamba kwambiri wa CO₂ kapena ukadaulo wa bio-enzymatic hydrolysis kuyeretsa asidi wa caffeic kuchokera kuzinthu zopangira mbewu, ndi chiyero chopitilira 98%, kukwaniritsa miyezo yamankhwala ndi zodzikongoletsera.
● Kodi Ubwino Wake Ndi Chiyani Caffeic Acid?
Caffeic acid imawonetsa zochitika zingapo zamoyo chifukwa cha o-diphenolic hydroxyl:
1. Antioxidant ndi Anti-kutupa:
Lili ndi mphamvu yamphamvu kwambiri yaufulu yothamangitsa pakati pa hydrogenated cinnamic acid, ndipo mphamvu yake ndi 4 kuchulukitsa kwa vitamini E. Imatchinga machitidwe a lipid peroxidation popanga mapangidwe a quinone;
Imalepheretsa kaphatikizidwe ka leukotriene (imayang'anira chitetezo chamthupi ndi kutupa), imachepetsa kuwonongeka kwa DNA ya UV-induced khungu, ndipo imachepetsa erythema index ndi 50%.
2. Kutetezedwa kwa Metabolic And Cardiovascular:
Caffeic acidImalepheretsa oxidation ya low-density lipoprotein (LDL) ndikuchepetsa mapangidwe a atherosclerotic plaque;
Poyesa mbewa zamafuta ambiri, kuchuluka kwamafuta a visceral kunatsika ndi 30% ndipo triglycerides yachiwindi idatsika ndi 40%.
3. Neuroprotection And Anti-Tumor:
Kupititsa patsogolo chizindikiro cha hippocampal insulini, kupititsa patsogolo kukumbukira ntchito mu zitsanzo za matenda a Alzheimer's, ndi kuchepetsa kuyika kwa mapuloteni a β-amyloid;
Imalepheretsa kuchuluka kwa maselo a khansa ya fibrosarcoma ndikuletsa kukula kwa chotupa mwa kuchepetsa DNA methylation.
4. Kuwonjezeka kwa Hemostasis ndi Leukocyte:
Imachepetsa ma microvessels ndikuwongolera magwiridwe antchito a coagulation factor. Amagwiritsidwa ntchito pochiza opaleshoni ya hemostasis ndi leukopenia pambuyo pa mankhwala amphamvu, ndi mphamvu yoposa 85%.
● Kodi Ma Applications Ndi Chiyani Caffeic Acid ?
Kugwiritsa ntchito caffeic acid kumakhudza mbali zambiri:
1. Mankhwala:mapiritsi a caffeic acid (hemostasis, kuchuluka kwa maselo oyera a magazi), anti-tumor targeted drug (succinic acid phase II clinical trial)
2. Zodzoladzola:sunscreen (synergistic zinc oxide kuonjezera mtengo wa SPF), whitening essence (inhibit tyrosinase, melanin inhibition rate 80%).
3. Makampani a Chakudya:zotetezera zachilengedwe (kuchedwetsa nsomba lipid oxidation), zakumwa zogwira ntchito (zotsutsa-oxidation ndi odana ndi kutupa), synergistic kugwiritsa ntchito ascorbic acid
4. Ulimi ndi Kuteteza Kwachilengedwe:mankhwala ophera tizilombo (kuletsa thonje bollworm protease), kusintha ubweya (antioxidant katundu wawonjezeka ndi 75%)
●Kagwiritsidwe Ntchito Ndi ChitetezoZaCaffeic Acid
Mlingo wamankhwala:Mapiritsi a Caffeic acid: 0.1-0.3g kamodzi, katatu pa tsiku, masiku 14 monga njira ya chithandizo, chiwerengero cha platelet chiyenera kuyang'aniridwa (kuchepetsedwa pamene> 100 × 10⁹/L, muyenera kukaonana ndi dokotala musanagwiritse ntchito);
Contraindications:Contraindicated kwa amayi apakati ndi odwala hypercoagulable boma; amagwiritsidwa ntchito mosamala odwala omwe ali ndi vuto la chiwindi ndi zilonda zam'mimba.
Zodzikongoletsera zowonjezera:0.5% -2% anawonjezera mankhwala whitening, chisanadze kusungunuka Mowa ndiyeno anawonjezera kuti masanjidwewo amadzimadzi kupewa agglomeration.
Zofunikira posungira:osindikizidwa m'malo amdima, firiji pa 2-8 ℃, yovomerezeka kwa zaka 2 (zokonzekera zamadzimadzi ziyenera kutetezedwa ku makutidwe ndi okosijeni ndi kuwonongeka)
●NEWGREEN SupplyCaffeic AcidUfa
Nthawi yotumiza: Jul-23-2025
