• Kodi N'chiyani?Bifidobacteria Longum ?
Bifidobacterium longum nthawi zonse yakhala ndi malo apakati pakufufuza kwaumunthu kwa ubale pakati pa tizilombo toyambitsa matenda ndi thanzi. Monga membala wochulukira kwambiri komanso wogwiritsidwa ntchito kwambiri pagulu la Bifidobacterium, kukula kwake kwa msika wapadziko lonse lapansi kukuyembekezeka kupitilira US $ 4.8 biliyoni mu 2025, ndikukula kwapachaka kwa 11.3%. Kafukufuku wa 2025 wofalitsidwa mu Nature Microbiology adatsimikizira kuti Bifidobacterium longum imatha kuwongolera machitidwe oda nkhawa kudzera m'matumbo a ubongo, kuwonetsa kuti "m'matumbo" uyu akukonzanso mawonekedwe azaumoyo mwanjira yatsopano.
Bifidobacterium longum: Gram-positive, non-spore-forming, ndipo mosamalitsa anaerobic, imakula bwino pa 36-38°C ndipo imalekerera pH ya 5.5-7.5. Kachulukidwe kake ka cell mu MRS chikhalidwe sing'anga amatha kufika 10 ^ 10 CFU/mL.
Kukonzekera kwa mafakitale: Pogwiritsa ntchito ukadaulo wa microencapsulation, kupulumuka kwa ma cell kumawonjezeka mpaka 92%.
• Ubwino Wake Ndi Chiyani?Bifidobacteria Longum?
Kutengera ndi maphunziro opitilira 3,000 padziko lonse lapansi, Bifidobacterium longum imawonetsa zamoyo zambiri:
1. Kusamalira Thanzi la M'matumbo
Microbiome Modulation: Imapondereza tizilombo toyambitsa matenda potulutsa ma peptides antimicrobial (monga bifidocin), kukulitsa kuchuluka kwa matumbo a bifidobacteria nthawi 3-5.
Kukonzekera kwa Mucosal: Imawongolera kufotokoza kwa mapuloteni a occludin, imachepetsa matumbo a m'mimba (FITC-dextran permeability yatsika ndi 41%), ndi kuchepetsa leaky gut syndrome.
2. Malamulo a Chitetezo cha mthupi
Cytokine Balance:Bifidobacteria longumimapangitsa kuti IL-10 ituluke (imapangitsa kuti chiwerengero cha 2.1 chiwonjezereke), imalepheretsa TNF-α (imachepetsa ndi 58%), ndipo imayambitsa matenda otupa.
Kulimbana ndi Matenda Osokoneza Bongo: Amachepetsa mlingo wa IgE wa seramu ndi 37% ndipo amachepetsa zochitika za atopic dermatitis mwa makanda ndi ana aang'ono (OR = 0.42).
3. Neuropsychiatric Modulation
Zotsatira za Gut-Brain Axis: Zimayendetsa njira ya mitsempha ya vagus, kuchepetsa nthawi yosambira yokakamiza mu mbewa zokhudzana ndi nkhawa ndi 53%. Kulowererapo kwa Metabolic: ma SCFAs (ma chain-chain mafuta acids) amawongolera zolandilira za GABA ndikuwongolera kugona kwa makoswe omwe amatengera kupsinjika kwakanthawi.
4. Kupewa ndi Kuchiza Matenda
Metabolic Syndrome: Kuchepetsa kusala kwa shuga m'magazi ndi 1.8 mmol / L mwa odwala omwe ali ndi matenda a shuga a 2 ndikuwongolera index ya HOMA-IR ndi 42%.
Chithandizo cha Khansa ya Adjuvant: Kuphatikiza ndi 5-FU kunachulukitsa kuchuluka kwa mbewa zokhala ndi khansa ya m'matumbo ndi 31% ndikuchepetsa kuchuluka kwa chotupa ndi 54%.
• Kodi Kugwiritsa Ntchito Ndi Chiyani?Bifidobacteria Longum ?
Bifidobacterium longum ikudutsa malire achikhalidwe, ndikupanga madera asanu ndi limodzi ogwiritsira ntchito:
1. Makampani a Chakudya
Zakudya zamkaka zothira: Zikaphatikizidwa ndi Streptococcus thermophilus, zimachulukitsa kukhuthala kwa yogurt ndi nthawi 2.3 ndikuwonjezera moyo wa alumali mpaka masiku 45.
Zakudya zogwira ntchito: Kuwonjezera 5 × 10 ^ 9 CFU / g ku mipiringidzo ya phala kumawonjezera mayendedwe a matumbo kuchokera ku 2.1 mpaka 4.3 pa sabata mwa anthu omwe ali ndi vuto la kudzimbidwa.
2. Mankhwala
Mankhwala Ogulitsira (OTC):Bifidobacteria longummakapisozi a mabakiteriya amoyo atatu (Lizhu Changle) ali ndi malonda apachaka opitilira mabokosi 230 miliyoni ndipo ndi othandiza 89% pochiza matenda otsekula m'mimba.
Biologics: Mapiritsi ang'onoang'ono osungunuka mwachangu amawonjezera liwiro la koloni katatu ndipo alandila chilolezo cha FDA Fast Track.
3. Ulimi ndi Chakudya
Kuweta ziweto ndi nkhuku: Kuonjezera 1 × 10 ^ 8 CFU/kg ya chakudya kumachepetsa kutsekula m'mimba mwa ana a nkhumba ndi 67% ndipo kumawonjezera kusintha kwa chakudya ndi 15%. Chitetezo cha Zomera: Kubzala kwa Rhizosphere kunachepetsa kunyala kwa bakiteriya wa phwetekere ndi 42% ndikuchulukitsa zokolola ndi 18%.
4. Zodzoladzola Zosakaniza
Kukonza Zotchinga: 0.1% yochotsera bakiteriya yachepetsa khungu TEWL (transepidermal water loss) ndi 38%, ndikulandira chiphaso cha EU ECOCERT.
Mapulogalamu Oletsa Kukalamba: Ophatikizidwabifidobacteria longumndi ma peptides, idachepetsa kuya kwa makwinya a periorbital ndi 29%, ndikulandila satifiketi yodzikongoletsera yogwiritsa ntchito mwapadera kuchokera ku Unduna wa Zaumoyo, Ntchito ndi Ubwino wa Japan.
5. Zamakono Zachilengedwe
Kuyeretsa Madzi Otayira: Kuwonongeka kwa Ammonia nitrogen kwa 78% kunatheka, kuchepetsa kupanga zinyalala ndi 35%.
Biofuel: Kupanga kwa asidi acetic kunakwera kufika pa 12.3 g/L, kuchepetsa mtengo ndi 40% poyerekeza ndi miyambo yakale.
6. Pet Health
Chakudya Chachiweto: Kuwonjezera 2 × 10 ^ 8 CFU / kg ku chakudya cha agalu kunapangitsa kuti chimbudzi chikhale bwino ndi 61% ndikuchepetsa kutsekula m'mimba.
Kusintha kwa Makhalidwe: Kupopera mbewu mankhwalawa kunachepetsa nkhawa zopatukana ndikuchepetsa khalidwe laukali ndi 54%.
• Newgreen Supply High QualityBifidobacteria LongumUfa
Nthawi yotumiza: Jul-29-2025
