●Gịnị bụ Zinc pyrithion?
Zinc pyrithione (ZPT) bụ ihe mgbagwoju anya zinc nke nwere usoro ihe omimi nke C₁₀H₈N₂O₂S₂Zn (molecular arọ 317.7). Aha ya sitere na ihe mgbọrọgwụ sitere n'okike nke osisi Annonaceae Polyalthia nemoralis, mana ụlọ ọrụ ọgbara ọhụrụ anabatala njikọ kemịkalụ iji mepụta ya. N'afọ 2024, usoro ikike ikike nke China mebiri n'olu dị ọcha, na crotonic acid na-adịghị ọcha na-achịkwa n'okpuru 16ppm site na methanol-acetone graded crystallization, na ọkwa ọkwa ọgwụ mụbara ruo 99.5%.
Njirimara anụ ahụ na kemịkal:
Ọdịdị na solubility: na-acha ọcha ka ọ dị ntakịrị odo crystalline ntụ ntụ, ọ fọrọ nke nta ka ọ ghara ịdị na mmiri (<0.1g / 100mL), ntakịrị soluble na ethanol, solubility na polyethylene glycol nwere ike iru 2000mg / kg;
Mkpebi nkwụsi ike: na-enwe mmetụta maka ìhè na oxidants, na-eweda ya ngwa ngwa site na ìhè ultraviolet, nkwakọ ngwaahịa aja aja chọrọ; ọdịda dissociation na pH <4.5 ma ọ bụ> 9.5, pH kacha mma bụ 4.5-9.5;
Thermal decomposition dị oke mkpa: kwụsiri ike maka 120 awa na 100 ℃, ma decomposes ngwa ngwa n'elu 240 ℃;
Enweghị ndakọrịta: na-ebuli elu na cationic surfactants, chelates na discolors na ígwè / ọla kọpa (ọbụlagodi 1ppm nwere ike ime ka ngwaahịa ahụ gbanwee odo odo).
●Kedu ihe bụUruNke Zinc pyrithion ?
ZPT na-enweta sterilization sara mbara (dị irè megide ụdị microorganisms 32) site na usoro mgbanwe ion pụrụ iche, ọkachasị maka Malassezia, onye na-eme dandruff, yana MIC dị ala dị ka 8ppm:
1. Ion Gradient mbibi
Na gburugburu acidic, H⁺ na-abanye n'ime nje bacteria na K⁺ na-emepụta, na na mpaghara alkaline, Na⁺ / Mg²⁺ na-edochi anya, nke na-emebi usoro ihe oriri na-edozi ahụ microbial;
2. Mgbochi mkpụrụ ndụ cell
Ịtinye n'ime bilayer phospholipid, na-abawanye permeability nke akpụkpọ ahụ ma na-eme ka ntapụ ihe onwunwe intracellular;
3. Mgbochi Ọrụ Enzyme
Na-egbochi yinye njem elektrọn na igbochi isi enzymes nke metabolism ike (dị ka ATP synthase).
Nyocha ụlọ ọgwụ: Mgbe ejiri ncha ntutu nwere 1.5%zincpyrthionemaka izu 4, a na-ebelata dandruff site na 90%, na nlọghachi azụ nke seborrheic dermatitis na-ebelata site na 60%.
●Kedu ihe bụNgwaOf Zinc pyrithion?
1. Ubi kemịkalụ kwa ụbọchị:
Enwere ike iji ya na 70% nke ncha ntutu na-egbochi dandruff, na mgbakwunye nke 0.3% -2%;
Ụfọdụ ngwaahịa ịchọ mma nwere ike igbochi ojiji nke zinc pyrithion na ọ dị mkpa ka edobe ya "sachapụ mgbe ejiri ya". Ị nwere ike iji ngwaahịa ọzọ piroctone ethanolamine (OCT).
2. Mgbochi corrosion ụlọ ọrụ:
Mgbanwe na-emebi emebi: jikọtara ya na cuprous oxide iji gbochie mgbakwunye barnacle ma belata oriri mmanụ ụgbọ mmiri site na 12%;
3. Agriculture na Akụrụngwa:
Nchekwa mkpụrụ: 0.5% ihe mkpuchi na-egbochi mildew ma na-abawanye ọnụego germination site na 18%;
eriri Antibacterial: akwa polyester anyadokwa nwere ọnụego nje nje> 99%.
4. Mgbatị ahụike:
Ihe kpatara ihe atọ kpatara ule na-adịghị mma (enweghị carcinogenicity / teratogenicity / mutagenicity), ejiri maka gel acne na mkpuchi antibacterial nke ngwaọrụ ahụike.
●Ndụmọdụ:
Ọ bụ ezie na nnukwu ọnụ toxicityof zinc pyrithiondị ala (LD₅₀>1000mg/kg na ụmụ oke), ịdọ aka ná ntị ụlọ ọgwụ n'afọ ndị na-adịbeghị anya:
Nsi akpụkpọ anụ: kọntaktị ogologo oge na-akpata nfụkasị dermatitis, na kọntaktị nkuchianaya nwere ike ịkpata conjunctivitis;
Ihe mgbochi zuru oke:
→ akpụkpọ ahụ gbajiri agbaji (permeability na-abawanye ugboro 3, na-ebute mkpughe usoro);
→ Ụmụ nwanyị dị ime na ụmụaka (data ihe mgbochi ụbụrụ ụbụrụ na-efu efu);
Mmekọrịta ọgwụ ọjọọ: Zenarị ijikọ ya na EDTA (chelating zinc ion na-ebelata nrụpụta ọgwụ).
●Ọdịmma dị elu NEWGREENZinc pyrithionNtụ ntụ
Oge nzipu: Jul-09-2025
