Minoxidil: Ngwa nke “ọgwụ uto ntutu ime anwansi”

●Gịnị bụ Minoxidil?

Na akụkọ mberede nke akụkọ ihe mere eme ahụike, minoxidil nwere ike na-ewere dị ka otu n'ime ihe ịga nke ọma "nchọpụta ihe mberede". Mgbe e mepụtara ya dị ka ọgwụ antihypertensive na 1960, mmetụta dị n'akụkụ hypertrichosis kpatara ya ghọrọ mgbanwe mgbanwe na ọgwụgwọ ntutu isi. Mgbe ihe fọrọ nke nta ka ọ bụrụ afọ 60 nke mmepe, onyinye a ewepụtala ọtụtụ ụdị usoro ọgwụgwọ dịka ngwọta, ụfụfụ, na gels. Ngụkọta ọnụ ọgụgụ dị irè nke 5% minoxidil na ọgwụgwọ telogen effluvium karịrị 80%, nke na-egosikwa ọzọ ikike ngosipụta ya.

Aha kemịkal nke minoxidil bụ 6- (1-piperidinyl) -2,4-pyrimidinediamine-3-oxide, nke nwere usoro ihe omimi nke C₉H₁₅N₅O, ebe agbaze nke 272-274℃, isi ihe na-esi esi nke 351.7℃, njupụta nke 11.65 g nke g. na-agbaze ngwa ngwa na ethanol na propylene glycol.

●Gịnị BụUruNke Minoxidil ?

Dabere na nyocha usoro ihe omimi, minoxidil na-egosipụta mmetụta dị iche iche nke ndu:

1. Vascular Dynamics

Na-arụ ọrụ ATP-sensitive potassium channels (KATP), na-eme ka uru ahụ dị nro dị nro ma na-eme ka ọbara na-eru n'isi site na 40%-60%.

Na-akwalite okwu VEGF, na-abawanye njupụta nke arịa ọbara ọhụrụ site na ugboro 2.3, ma na-eme ka nri na-edozi ahụ nke ntutu isi dịkwuo mma.

2. Iwu nke okirikiri ntutu isi

Mee ka usoro izu ike dị mkpụmkpụ (site na 100 ụbọchị ruo ụbọchị 40) wee mee ka usoro uto ahụ dịkwuo ogologo karịa ụbọchị 200.

Minoxidilnwere ike mee ka ụzọ Wnt/β-catenin rụọ ọrụ, ma na-abawanye ụba nke mkpụrụ ndụ papilla ntutu site na 75%.

3. Mmelite nke Microenvironment Mpaghara

Na-egbochi ọrụ 5a-reductase, na-ebelata ntinye DHT site na 38%, ma na-ebelata alopecia androgenic.

Na-achịkwa ihe ndị na-akpasu iwe dị ka IL-6 na TNF-α, ma na-ebelata ọnụ ọgụgụ mbufụt nke isi site na 52%.

●Gịnị BụNgwaOf Minoxidil?

Minoxidil na-agbaji n'ókè nke ihe ngosi ọdịnala:

1. Ọgwụ ntutu

Androgenetic alopecia: 5% ngwọta na-emeso AGA nwoke, na ọnụ ọgụgụ mkpuchi ntutu na-abawanye site na 47% na ọnwa 12.

Alopecia areata: Nnyocha ndị Japan mere na 2025 gosiri na ịdị irè nke ndị na-egbochi JAK jikọtara ọnụ sitere na 35% ruo 68% jiri otu ọgwụ.

2. Mweghachi akpụkpọ ahụ

Ọnya ụkwụ na-arịa ọrịa shuga: Ngwa mpaghara na-eme ka ọgwụgwọ ọnya dị ngwa ma na-ebelata oge ọgwụgwọ site na 30%.

Nrụzi Scar: Na-egbochi okwu TGF-β1 ma na-ebelata isi ike site na 42%.

3. Agriculture and Environmental Protection

Usoro nhazi ihe ọkụkụ: 0.1ppm ngwọta na-agwọ osikapa, ọnụ ọgụgụ nke ndị na-akụ ihe na-abawanye site na 18%.

Ndozi ala: arụmọrụ nke adsorption nke cadmium metal dị arọ ruru 89%, nke a na-eji maka mweghachi gburugburu ebe obibi na mpaghara Ngwuputa.

●Akpachara anyankeMinoxidil Maka iji ogologo oge

Ihe nleba anya: Na-enyocha ọbara mgbali elu na ọnụ ọgụgụ obi mgbe niile, karịsịa maka ndị nwere ọrịa obi;

Otu dị iche iche: A machibidoro ụmụ nwanyị dị ime, ụmụ nwanyị na-enye nwa ara, na ndị nwere ihe nfụkasị na propylene glycol;

Nhọrọ nke usoro onunu ogwu: 5% itinye uche na-atụ aro maka ụmụ nwoke, na 2% nwere ike ịhọrọ maka ụmụ nwanyị iji belata mmetụta ndị ọzọ;

Ọgwụgwọ jikọtara ọnụ: Enwere ike ijikọta ntutu isi siri ike na finasteride (maka ụmụ nwoke) ma ọ bụ ọgwụgwọ laser dị ala.

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● Ọdịmma nke Newgreen Supply MinoxidilNtụ ntụ