● Gịnị BụHydroxycitric acid ?
Hydroxycitric acid (HCA) bụ isi ihe na-arụ ọrụ na bee Garcinia cambogia. Ọdịdị kemịkal ya bụ C₆H₈O₈ (dị arọ molecular 208.12). Ọ nwere otu hydroxyl ọzọ (-OH) na ọnọdụ C2 karịa citric acid nkịtị, na-eme ikike nhazi usoro metabolic pụrụ iche. Garcinia cambogia bụ obodo India na Ndịda Ebe Ọwụwa Anyanwụ Eshia. A na-eji bee ya akpọnwụwo ogologo oge dị ka ihe na-esi ísì ụtọ, na teknụzụ mmịpụta ọgbara ọhụrụ nwere ike itinye 10%-30% nke HCA site na ya. Na 2024, teknụzụ ikike ikike nke China (CN104844447B) mụbara ịdị ọcha ruo 98% site na mmịpụta dị elu na-ekpo ọkụ + nanofiltration desalination usoro, na-edozi nsogbu nke adịghị ọcha residues na omenala acid hydrolysis.
Njirimara anụ ahụ na kemịkalụ nke Hydroxycitric Acid:
Ọdịdị: ọcha na-acha odo odo crystalline ntụ ntụ, uto utoojoo;
Solubility: mfe soluble na mmiri (> 50mg / mL), ubé soluble na ethanol, insoluble na-abụghị polar solvents;
Nkwụsi ike: na-enwe mmetụta maka ọkụ na okpomọkụ, dị mfe imebi mgbe pH <3, ọ dị mkpa ka echekwara ya pụọ na ìhè na obere okpomọkụ (<25 ℃);
Ọkọlọtọ nchọpụta: chromatography mmiri mmiri dị elu (HPLC) iji chọpụta ọdịnaya, ịdị ọcha nke wepụ HCA dị elu kwesịrị ịbụ ≥60%.
●Gịnị Bụ Uru ỌbaraHydroxycitric acid ?
HCA na-enweta mfu abụba site n'ụzọ atọ, ma dabara adaba maka ndị nọ na nri nwere nnukwu carbohydrate:
1. Inhibit Fat Synthesis
Na-asọmpi na-ejikọta ATP-Citrate Lyase, na-egbochi ụzọ acetyl-CoA ka ọ ghọọ abụba;
Nnyocha ụlọ ọgwụ egosila na ọ na-ebelata njikọ abụba site na 40%-70% n'ime awa 8-12 mgbe nri gasịrị.
2. Kwalite abụba ọkụ
Na-arụ ọrụ ụzọ akara AMPK ma na-eme ka fatty acid β-oxidation dịkwuo elu na akwara na imeju;
Nkezi pasentị abụba anụ ahụ nke ihe ejirila 2.3% belata na nnwale izu iri na abụọ.
3. Mezie agụụ
Mmụba ụbụrụ serotonin (5-HT) ọkwa ma belata oriri calorie dị elu;
Na-ejikọta ya na cellulose osisi iji mee ka afọ ju afọ.
●Gịnị bụ ngwa nkeHydroxycitric acid ?
1. Njikwa ibu:
Dị ka isi ihe dị na capsules na-efunahụ ibu na ntụ ntụ dochie nri, a na-atụ aro dose bụ 500-1000 mg / ụbọchị (ewere ya ugboro 2-3);
Ejikọtara ya na L-carnitine na caffeine, ọ nwere ike ịkwalite mmetụta ọkụ abụba.
2. Nri egwuregwu:
Mee ka ntachi obi dịkwuo mma ma belata ike ọgwụgwụ mgbe mgbatị ahụ gasịrị, nke kwesịrị ekwesị maka ndị na-eme egwuregwu na ndị ahụ dị mma.
3. Ahụ Ike Metabolic:
Mee ka mmetụta insulin dịkwuo elu ma nyere aka n'ịhazi shuga ọbara na lipids ọbara (LDL-C na-ebelata ihe dịka 15%).
4.Food Industry:
Dị ka acidifier eke eji eme ihe ọṅụṅụ na-enweghị shuga, ọ nwekwara ọrụ nke ịhazi metabolism.
● Ndụmọdụ:
1. Mmeghachi omume ọjọọ:
Nnukwu doses nkehydroxycitric acid(> 3000mg / ụbọchị) nwere ike ime ka isi ọwụwa, ọgbụgbọ, na ahụ erughị ala nke eriri afọ;
Iji ogologo oge na-achọ nlekota ọrụ imeju (n'ọnọdụ ole na ole a kọrọ na transaminases dị elu).
2. Contraindications:
Ụmụ nwanyị dị ime na ụmụ nwanyị na-enye nwa ara (data nchekwa ezughị oke);
Ndị ọrịa nwere ọrịa shuga (nchịkọta ọgwụ hypoglycemic nwere ike ibute hypoglycemia);
Ndị na-eji ọgwụ psychotropic (iwu 5-HT nwere ike imetụta nrụpụta ọgwụ).
3. Mmekọrịta ọgwụ:
Zere ijikọ ya na antidepressants (dị ka SSRIs) iji gbochie ihe ize ndụ nke ọrịa 5-HT.
●Ọhụrụgreen ọkọnọ dị eluHydroxycitric acidNtụ ntụ
Oge nzipu: Jul-08-2025
