●Gịnị bụ Chondroitin sulfate sodium?
Chondroitin sulfate Sodium (CSS) bụ mucopolysaccharide acid sitere n'okike nwere usoro kemịkalụ nke C₄₂H₅₇N₃Na₆O₄₃S₃X₂ (ihe dị ka 1526.03 dị arọ). A na-ewepụtakarị ya site na anụ ahụ cartilage nke anụmanụ dị ka ezì, ehi, na shark. Ihe mejupụtara ya mejupụtara D-glucuronic acid ọzọ na N-acetylgalactosamine, nwere nkeji 50-70 disaccharide ma buru otu acetyl na sulfate nha nha. Ihe ndị dị n'elu ka na-adabere na cartilage ọhụrụ dị obere okpomọkụ, n'ime nke ọkpụkpụ anụ ezi na ọkpụkpụ etiti imi bụ nhọrọ mbụ maka mmepụta ọkwa ahụike n'ihi nnukwu ọdịnaya chondroitin sulfate A / C (na-aza ihe karịrị 24% nke akọrọ).
Usoro mmịpụtaof Chondroitin sulfate sodium:
Mwepụta ọdịnala chọrọ usoro anọ ziri ezi:
Deproteinization Alkaline: Sook cartilage na 2% sodium hydroxide ngwọta wee wepụ ya na mkpali na ụlọ okpomọkụ.
Enzymatic sachapụ: Hydrolyze na pancreatic enzymes na 53-54 ℃ maka awa 7, na adsorb adịghị ọcha na carbon arụ ọrụ;
Ọdịda Ethanol: Gbanwee pH na 6.0 ma gbakwunye 75% ethanol ka ọ daa;
akpịrị ịkpọ nkụ na nkụ: saa na ethanol anhydrous ma kpoo na oghere na 60-65 ℃.
Nkwalite usoro: Ọtụtụ ụlọ ọrụ ewepụtala akụrụngwa ahụike ọhụrụ-ọkwa akụrụngwa, na-eji cartilage shark maka mmịpụta, ịgafe nkwenye inactivation nje na usoro aseptic, yana ule pyrogen na cytotoxicity iji mezuo ụkpụrụ mba ụwa.
●Kedu ihe bụUruNke Chondroitin sulfate sodium ?
1. Isi Ọgwụgwọ Ọrịa nkwonkwo
Ndozi cartilage: na-akpali chondrocytes ka ọ na-emepụta collagen, meziwanye viscoelasticity mmiri synovial, ma belata esemokwu nkwonkwo na ndị ọrịa osteoarthritis site na 40%;
Mgbochi mgbu na-egbu egbu: na-egbochi phospholipase A2 na matrix metalloproteinases, belata mmepụta nke ndị mgbasa ozi mkpali dị ka prostaglandins, na nkwụsị mgbu na-erute 90% mgbe izu iri na abụọ gasịrị.
2. Usoro usoro obi obi
Mbelata egbugbere ọnụ na nchebe vaskụla: wepụ ihe nkwụnye lipid na mgbidi vaskụla, belata cholesterol plasma nke ukwuu, wee belata ebe plaques atherosclerotic site na 60%;
Anticoagulation: Ọrụ anticoagulant nkeChondroitin sulfate sodium bụ 0.45 ugboro / mg nke heparin, a na-egbochikwa thrombosis site na usoro fibrinogen.
3. Ntinye aka nke Ọrịa Cross-System
Nchedo anụ ihe: rụkwaa mkpụrụ ndụ ntutu isi cochlear, yana ọnụ ọgụgụ dị irè nke igbochi ntị chiri nke streptomycin kpatara karịrị 85%;
Ngwa ophthalmic: melite metabolism mmiri corneal, ma na-abawanye mmiri mmiri nke ndị ọrịa nwere anya nkụ site na 50%;
Ike mgbochi tumo: chondroitin sulfate nke shark nwetara na-egbochi metastasis nke mkpụrụ ndụ kansa site na igbochi tumor angiogenesis.
●Kedu ihe bụNgwaOf Chondroitin sulfate sodium?
1. Ahịa Na-achị Na-ahụ Maka Ọgwụ Na-ahụ Maka Ọgwụ
Nlekọta ahụike nkwonkwo: nkwadebe jikọtara ya na glucosamine maka 45% nke ahịa ọgwụ osteoarthritis zuru ụwa ọnụ.
Ọgwụ gbasara obi: nchịkwa ọnụ kwa ụbọchị nke 0.6-1.2g nwere ike ibelata ọnụọgụ ọnwụ nke ọrịa obi obi site na 30%
2. Ngwa ahụike na ihe ọhụrụ aesthetics ahụike
Ophthalmic viscoelastics: ịdị ọcha dị eluchondroitin sulfate sodiuma na-eji ya na ịwa ahụ cataract iji chebe ọnụego ndụ nke mkpụrụ ndụ endothelial corneal karịa 95%;
Ndị na-ahụ maka ahụike ahụike: enwere ike iji ya dị ka akụrụngwa injection-ọkwa na-adịghị mma maka ịgbanye ọkụ mmiri na ndochi dermal, na-akwalite nrụpụta nrụpụta collagen site na 70%;
Ọgwụgwọ ọnya: 0.2% gel na-eme ngwa ngwa ọgwụgwọ nke ọnya ụkwụ na-arịa ọrịa shuga, ọnụ ọgụgụ ọnya ahụ na-ebelata n'ime ụbọchị 21 ruru 80%.
3. Mgbatị nke ngwaahịa ndị ahịa na-arụ ọrụ
Nlekọta akpụkpọ ahụ na mgbochi ịka nká: Ịtinye ya na ude nwere ike ime ka ọdịnaya anụ ahụ dịkwuo 16% ma belata omimi nke wrinkles site na 29%;
Nri ahụike: Otu ụlọ ọrụ bidoro swiiti dị nro na-arụ ọrụ "CSS+ mmanụ azụ" iji hazie mgbanwe nkwonkwo na ọkwa lipid ọbara n'otu oge.
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●Ọdịmma dị elu nke Newgreen Chondroitin sulfate sodium Ntụ ntụ
Oge nzipu: Ọgọst-12-2025
