Bifidobacterium Longum: Tus Saib Xyuas Ntawm Txoj hnyuv

• Dab tsi yogBifidobacterium Longum ?

Bifidobacterium longum yeej ib txwm tuav txoj haujlwm tseem ceeb hauv tib neeg txoj kev tshawb nrhiav kev sib raug zoo ntawm microbes thiab kev noj qab haus huv. Raws li cov neeg siv ntau tshaj plaws thiab siv dav ntawm Bifidobacterium genus, nws cov lag luam thoob ntiaj teb yog kwv yees kom tshaj US $ 4.8 nphom hauv 2025, nrog rau kev loj hlob txhua xyoo ntawm 11.3%. Ib txoj kev tshawb fawb xyoo 2025 tau tshaj tawm hauv Nature Microbiology tau lees paub tias Bifidobacterium longum tuaj yeem tswj hwm kev ntxhov siab ntawm lub plab-hlwb axis, qhia tias "cov neeg hauv plab hnyuv" no tau hloov kho cov kev lag luam kev noj qab haus huv hauv qhov tshiab.

Bifidobacterium longum: Gram-positive, non-spore-forming, thiab nruj me ntsis anaerobic, nws loj hlob zoo ntawm 36-38 ° C thiab ua siab ntev pH ntau ntawm 5.5-7.5. Nws qhov kev siv tau ntawm tes ceev hauv MRS kab lis kev cai nruab nrab tuaj yeem ncav cuag 10 ^ 10 CFU / mL.

Kev npaj muaj: Siv cov tshuab microencapsulation, cov cell ciaj sia taus nce mus txog 92%.

• Cov txiaj ntsig yog dab tsiBifidobacterium Longum?

Raws li ntau dua 3,000 kev tshawb fawb thoob ntiaj teb, Bifidobacterium longum ua rau pom muaj ntau yam teebmeem lom neeg:

1. Kev Tswj Xyuas Kev Noj Qab Haus Huv Gut

Microbiome Modulation: Nws suppresses pathogens los ntawm secreting antimicrobial peptides (xws li bifidocin), ua kom cov plab hnyuv bifidobacteria ntau ntau los ntawm 3-5 zaug.

Mucosal Kho: Nws upregulates occludin protein qhia, txo txoj hnyuv permeability (FITC-dextran permeability txo los ntawm 41%), thiab alleviates leaky plab syndrome 

2. Kev cai tiv thaiv kab mob

Cytokine Balance:Bifidobacterium longumstimulates IL-10 secretion (nce concentration los ntawm 2.1 zaug), inhibits TNF-α (txo 58%), thiab txhim kho cov kab mob plab hnyuv. 

Kev Tiv Thaiv Kev Ua xua: Nws txo cov ntshav IgE los ntawm 37% thiab txo qhov tshwm sim ntawm atopic dermatitis hauv cov menyuam mos thiab cov menyuam yaus (OR = 0.42).

3. Neuropsychiatric Modulation

Gut-Brain Axis Effects: Nws qhib txoj hauv kev vagus paj hlwb, txo cov sij hawm yuam kev ua luam dej hauv cov nas muaj kev ntxhov siab los ntawm 53%. Kev cuam tshuam metabolic: SCFAs (cov saw hlau luv fatty acids) tswj GABA receptors thiab txhim kho kev pw tsaug zog zoo hauv nas ua qauv kev ntxhov siab.

4. Kev Tiv Thaiv Kab Mob thiab Kev Kho Mob

Metabolic Syndrome: Txo cov ntshav qabzib sai ntawm 1.8 mmol / L hauv cov neeg mob ntshav qab zib hom 2 thiab txhim kho HOMA-IR Performance index los ntawm 42%.

Adjuvant Cancer Therapy: Kev sib xyaw nrog 5-FU nce qhov ciaj sia ntawm cov nas uas muaj kab mob qog noj ntshav los ntawm 31% thiab txo cov qog nqaij hlav los ntawm 54%.

• Dab tsi yog Daim Ntawv Thov NtawmBifidobacterium Longum ?

Bifidobacterium longum tab tom tawg los ntawm ib txwm ciam teb, tsim rau rau qhov chaw thov loj:

1. Kev lag luam zaub mov

Cov khoom noj fermented: Thaum ua ke nrog Streptococcus thermophilus, nws ua rau yogurt viscosity nce 2.3 npaug thiab txuas lub neej txee rau 45 hnub.

Cov khoom noj muaj txiaj ntsig: Ntxiv 5 × 10^9 CFU / g rau cov khoom noj khoom haus ua kom lub plab zom mov ntau zaus ntawm 2.1 txog 4.3 zaug hauv ib lub lis piam hauv cov neeg mob cem quav.

2. Pharmaceuticals

Cov tshuaj hauv khw muag khoom (OTC):Bifidobacterium longumtriple live bacteria capsules (Lizhu Changle) muaj kev muag khoom txhua xyoo ntau tshaj 230 lab lub thawv thiab muaj 89% zoo hauv kev kho mob raws plab.

Biologics: Sublingual fast-dissolving ntsiav tshuaj nce probiotic colonization ceev los ntawm peb zaug thiab tau txais kev pom zoo FDA Fast Track.

3. Ua liaj ua teb thiab pub

Tsiaj txhu thiab nqaij qaib ua liaj ua teb: Ntxiv 1 × 10^8 CFU / kg ntawm pub kom txo tau raws plab hauv piglets los ntawm 67% thiab nce kev hloov pauv hloov pauv ntawm 15%. Kev Tiv Thaiv Cov Nroj Tsuag: Rhizosphere cog txo cov txiv lws suav cov kab mob wilt los ntawm 42% thiab nce tawm los ntawm 18%.

4. Cov khoom xyaw tshuaj pleev ib ce

Kev Kho Kev Kho Vaj Tse: 0.1% cov kab mob extract txo cov tawv nqaij TEWL (transepidermal dej poob) los ntawm 38%, tau txais daim ntawv pov thawj EU ECOCERT.

Anti-Aging Applications: Ua kebifidobacterium longumnrog peptides, nws txo qhov tob ntawm periorbital wrinkles los ntawm 29%, tau txais ntawv pov thawj tshwj xeeb siv tshuaj pleev ib ce los ntawm Nyiv Ministry of Health, Labor thiab Welfare.

5. Environmental Technology

Kev kho dej khib nyiab: Ammonia nitrogen degradation efficiency ntawm 78% tau tiav, txo cov sludge ntau lawm los ntawm 35%.

Biofuel: Acetic acid ntau lawm efficiency nce mus rau 12.3 g / L, txo cov nqi los ntawm 40% piv rau cov txheej txheem ib txwm muaj.

6. Pet Health

Cov Khoom Noj Tsiaj: Ntxiv 2 × 10^8 CFU / kg rau cov zaub mov dev txhim kho cov qhab nia ntawm 61% thiab txo qis raws plab.

Kev hloov pauv tus cwj pwm: Cov tshuaj tsuag tshem tawm kev ntxhov siab sib cais thiab txo tus cwj pwm nruj los ntawm 54%.

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