● He ahaThiamine Hydrochloride ?
ʻO ka Thiamine hydrochloride ka ʻano hydrochloride o ka huaʻa B₁, me ke ʻano kemika C₁₂H₁₇ClN₄OS·HCl, ke kaumaha molekala 337.27, a me ka helu CAS 67-03-8. He pauda kristal keʻokeʻo keʻokeʻo a melemele-keʻokeʻo me ka ʻala ʻala o ka laiki a me ka ʻono ʻawaʻawa. He mea maʻalahi ke komo i ka wai ma kahi maloʻo (hiki iā ia ke hoʻomoʻi i ka 4% moisture ke ʻike ʻia i ka ea). ʻO nā waiwai nui o ke kino a me ke kemika:
Hiki ke hoʻoheheʻe:Hiki ke hoʻoheheʻe ʻia i loko o ka wai (1g/mL), hiki ke hoʻoheheʻe ʻia i ka ethanol a me ka glycerol, a hiki ʻole ke hoʻoheheʻe ʻia i loko o nā mea hoʻoheheʻe kūlohelohe e like me ka etera a me ka benzene.
Paʻa:Paʻa i loko o kahi ʻakika (pH 2-4) a hiki ke kū i nā wela kiʻekiʻe o 140 ° C; akā, e hoʻoheheʻe koke ʻia i loko o nā hoʻonā kūʻokoʻa a i ʻole ka alkaline a hiki ke hoʻopau ʻia e nā kukuna ultraviolet a i ʻole nā mea hana redox.
Nā hiʻohiʻona ʻike:Hoʻopili ʻo ia me ka ferric cyanide e hoʻohua i kahi mea ʻulaʻula ʻulaʻula "thiochrome", a lilo ia i kumu no ka loiloi quantitative38.
ʻO ke kaʻina hana hoʻomākaukau nui o ka honua he chemical synthesis, e hoʻohana ana i ka acrylonitrile a i ʻole β-ethoxyethyl propionate ma ke ʻano he kumu waiwai a hana ʻia ma o ka condensation, cyclization, hoʻololi a me nā hana ʻē aʻe, me ka maʻemaʻe o ka 99%.
●He aha nā pōmaikaʻi oThiamine Hydrochloride ?
Hoʻololi ʻia ʻo Thiamine hydrochloride i ke ʻano ikaika o ka thiamine pyrophosphate (TPP) i loko o ke kino kanaka, a hoʻokani i nā hana physiological he nui:
1. ʻO ke kumu o ka ikehu:ma ke ʻano he coenzyme o ka α-ketoacid decarboxylase, komo pololei ia i ke kaʻina hana o ka hoʻololi ʻana o ka glucose i ATP. Ke hemahema, alakaʻi ia i ka hōʻiliʻili pyruvate, e hoʻoulu ai i ka lactic acidosis a me ka pilikia o ka ikehu.
2. Ka pale ʻana i nā ʻōnaehana nerve:Ka mālama ʻana i ka hana maʻamau o nā aʻalolo. ʻO ka hemahema nui ke kumu o ka beriberi, me nā hōʻailona maʻamau e like me ka neuritis peripheral, muscular atrophy, a me ka pau ʻole o ka naʻau. ʻO ka mōʻaukala, ua hana ia i kahi maʻi maʻi nui ma Asia, e pepehi ana i nā haneli haneli o nā kānaka i kēlā me kēia makahiki.
3. Ka waiwai noiʻi e puka mai ana:
Ka mālama ʻana i ka myocardial:Hiki i ka 10μM ka hoʻonui ʻana i ka antagonize acetaldehyde-induced myocardial cell damage, inhibiting caspase-3 activation, a hōʻemi i ka hoʻokumu ʻana o ka protein carbonyl.
Anti-neurodegeneration:I nā hoʻokolohua holoholona, hiki i ka hemahema ke alakaʻi i ka hōʻiliʻili ʻana o ka protein β-amyloid i loko o ka lolo, e pili ana i ka pathology o ka maʻi o Alzheimer.
ʻO nā pūʻulu pilikia nui no ka hemahema, penei:ka hoʻohana lōʻihi o ka laiki keʻokeʻo i hoʻomaʻemaʻe ʻia a me ka palaoa, nā mea inu waiʻona (ethanol inhibits thiamine absorption), nā wahine hāpai, a me nā mea maʻi me ka maʻi maʻi maʻi.
●He aha ka hoʻohana ʻana oThiamine Hydrochloride ?
1. ʻOihana meaʻai (mahele nui loa):
Nā mea hoʻonui meaʻai:hoʻohui ʻia i nā huahana cereal (3-5mg/kg), meaʻai pēpē (4-8mg/kg), a me nā mea inu waiu (1-2mg/kg) e hoʻihoʻi i ka nalowale o nā meaʻai ma muli o ka hana maikaʻi.
Nā pilikia ʻenehana:Ma muli o ka maʻalahi o ka decompose i loko o kahi ʻano alkaline, hoʻohana pinepine ʻia nā derivatives e like me thiamine nitrate i mea pani i nā meaʻai i kālua ʻia.
2. kahua lapaʻau:
Nā hoʻohana lāʻau lapaʻau:Hoʻohana ʻia nā injections no ka mālama ʻana i ka beriberi (neurological / heart failure), a hoʻohana ʻia nā hoʻomākaukau waha ma ke ʻano he kōkua kōkua no ka neuritis a me ka ʻai ʻana.
Hoʻoponopono hui:hui pū ʻia me nā mea hana magnesium e hoʻomaikaʻi i ka pono o Wernicke encephalopathy a hoʻemi i ka helu hoʻihoʻi.
3. Mahiai a me biotechnology:
ʻO nā mea hoʻoikaika kūʻē i ka maʻi hua:50mM ka mālama ʻana i ka laiki, nā kukama, a me nā mea ʻē aʻe.
Nā mea hoʻohui hānai:E hoʻomaikaʻi i ka maikaʻi o ka metabolism kō i loko o nā holoholona a me nā moa, ʻoi aku hoʻi i nā wahi koʻikoʻi wela (hoʻonui ʻia ke koi no ka excretion sweat).
● Hāʻawi ʻo NEWGREEN i ke ʻano kiʻekiʻeThiamine HydrochloridePauda
Ka manawa hoʻouna: Iune-30-2025
