●He aha ka ʻAka Caffeic?
ʻO ka ʻakika Caffeic, ka inoa kemika 3,4-dihydroxycinnamic acid (molecular formula C₉H₈O₄, CAS No. 331-39-5), he pūhui phenolic acid maoli i ʻike nui ʻia i nā mea kanu. He aniani melemele kona helehelena, hiki ke hoʻoheheʻe ʻia i ka wai anuanu, hiki ke hoʻoheheʻe ʻia i ka wai wela, ka ethanol a me ka ethyl acetate, me kahi helu heheʻe o 194-213 ℃ (ʻokoʻa nā kaʻina hana), ʻalani-ʻulaʻula i ka hopena alkaline, a me ka ʻōmaʻomaʻo ʻeleʻele e pili ana me ka ferric chloride.
Loaʻa nā kumu hoʻoheheʻe kumu:
●Nā mea kanu lāʻau:Asteraceae Solidago, kinamona, dandelion (loaʻa ka waika caffeic ≥ 0.02%), Ranunculaceae Cimicifuga rhizome;
●Nā kumuwaiwai huaʻai a me nā mea kanu:lemon peel, blueberry, apple, broccoli a me nā mea kanu cruciferous;
●Mea inu mea inu:nā pīni kope (ma ke ʻano o ka chlorogenic acid esters), ka waina (conjugated me ka tartaric acid).
Hoʻohana ka ʻenehana hou i ka ʻenehana CO₂ supercritical a i ʻole ka ʻenehana hydrolysis bio-enzymatic e hoʻomaʻemaʻe i ka waika caffeic mai nā mea kanu mea kanu, me ka hoʻomaʻemaʻe ʻoi aku ma mua o 98%, e hālāwai ana i nā kūlana lāʻau lapaʻau a me ka cosmetic.
● He aha nā pono o ʻAka Caffeic?
Hōʻike ka ʻakika Caffeic i nā hana olaola ma muli o kāna ʻano o-diphenolic hydroxyl:
1. Antioxidant A me Anti-Inflammatory:
Loaʻa iā ia ka ikaika loa o ka radical free scavenging hiki ma waena o ka hydrogenated cinnamic acid, a ʻo kona pono he 4 mau manawa ma mua o ka huaora E. Hoʻopaʻa ʻo ia i ka lipid peroxidation chain reactions ma ka hana ʻana i nā hale quinone;
Kāohi i ka leukotriene synthesis (hoʻoponopono i ka palekana a me ka mumū), hoʻemi i ka pōʻino DNA o ka ʻili i hoʻoiho ʻia e UV, a hoʻemi i ka index erythema e 50%.
2. Palena Metabolic a Cardiovascular:
ʻakika caffeineKāohi i ka lipoprotein haʻahaʻa haʻahaʻa (LDL) oxidation a hōʻemi i ka hoʻokumu ʻana o ka atherosclerotic plaque;
Ma nā hoʻokolohua ʻiole meaʻai momona nui, ua emi iho ka nui o ka momona visceral e 30% a ua hoʻemi ʻia nā triglycerides ate e 40%.
3. Neuroprotection a me ka anti-tumor:
Hoʻonui i ka hōʻailona insulin hippocampal, hoʻomaikaʻi i ka hana hoʻomanaʻo i nā ʻano maʻi o Alzheimer, a hoʻemi i ka waiho ʻana o ka protein β-amyloid;
Kāohi i ka hoʻonui ʻana o nā maʻi maʻi fibrosarcoma a pale i ka ulu ʻana o ka maʻi maʻi ma o ka hōʻemi ʻana i ka methylation DNA.
4. Mahuahua Hemostasis a me Leukocyte:
Hoʻemi ia i nā microvessels a hoʻomaikaʻi i ka hana o nā kumu coagulation. Hoʻohana ʻia ia no ka hemostasis surgical a me ka leukopenia ma hope o ka chemotherapy, me ka helu kūpono o ka 85%.
● He aha nā noi o ʻAka Caffeic ?
ʻO ka hoʻohana ʻana i ka waika caffeic e uhi i nā ʻano he nui:
1. Lapaʻau:nā papa ʻakika caffeic (hemostasis, hoʻonui ʻia ke koko keʻokeʻo), nā lāʻau anti-tumor i hoʻopaʻa ʻia (succinic acid phase II clinical trial)
2. Mea hoʻonani:pale lā (synergistic zinc oxide e hoʻonui i ka waiwai SPF), keʻokeʻo keʻokeʻo (inhibit tyrosinase, melanin inhibition rate 80%)
3. ʻOihana Meaʻai:nā mea mālama kūlohelohe (hoʻopaneʻe i ka lipid oxidation iʻa), nā mea inu hana (anti-oxidation a me anti-inflammatory), hoʻohana synergistic o ka ascorbic acid
4. Mahiai a me ka hoomalu kaiapuni:nā lāʻau pesticides kaiaola (ke pale i ka pulupulu bollworm protease), ka hoʻololi ʻana i ka huluhulu (nā waiwai antioxidant i hoʻonui ʻia e 75%)
●Hoʻohana a me nā hoʻoponopono palekanaNoʻAka Caffeic
Mea lāʻau lapaʻau:ʻO nā papa waika caffeic: 0.1-0.3g hoʻokahi, 3 mau manawa i ka lā, 14 mau lā ma ke ʻano o ka mālama ʻana, pono e nānā ʻia ka helu platelet (e hoʻemi ʻia i ka wā> 100 × 10⁹/L, pono e nīnau i ke kauka ma mua o ka hoʻohana ʻana);
Contraindications:Contraindicated no nā wahine hāpai a me nā mea maʻi me ke kūlana hypercoagulable; Hoʻohana ʻia me ka akahele i nā poʻe maʻi me ka maʻi ʻeha a me nā maʻi ʻeha o ka ʻōpū.
Nā mea hoʻohui nani:0.5% -2% i hoʻohui ʻia i nā huahana keʻokeʻo, hoʻoheheʻe mua ʻia i ka ethanol a laila hoʻohui ʻia i ka matrix aqueous e pale i ka agglomeration.
Pono e mālama:hoʻopaʻa ʻia i kahi wahi pouli, hoʻopaʻa ʻia i ka 2-8 ℃, kūpono no 2 mau makahiki (pono e pale ʻia nā hoʻomākaukau wai mai ka oxidation a me ka degradation)
●Hoolako NU HOUʻAka CaffeicPauda
Ka manawa hoʻouna: Jul-23-2025
