●He aha ka Andrographis Paniculata Extract?
ʻO Andrographis paniculata, i kapa ʻia ʻo "hoʻokahi manawa hauʻoli" a me ka "mauʻu ʻawaʻawa", he mea kanu lāʻau makahiki o ka ʻohana Acanthaceae. He kanaka maoli ia no Asia Hema e like me India a me Sri Lanka, a ua laha nui ia i keia manawa ma na wahi wela a me Guangdong a me Fujian ma Kina. ʻOi aku ka ʻawaʻawa o ka mea kanu holoʻokoʻa, me kahi ʻāpana ʻāpana, nā lau ʻē aʻe, a me ka wā pua o ʻAukake-Sepatemaba. Hoʻohana ka lāʻau lapaʻau kuʻuna Kina i kona hopena o ka hoʻomaʻemaʻe ʻana i ka wela a me ka hoʻomaʻemaʻe ʻana, ka hoʻomaʻalili ʻana i ke koko a me ka hoʻohaʻahaʻa ʻana i ka pehu no ka mālama ʻana i ke anu, ke kuni, ka maʻi ʻeha, nā ʻeha a me nā nahu nahesa. Hoʻopuka ka ʻoihana hou i nā mea ikaika mai nā kumu a me nā lau ma o ka supercritical CO₂ extraction a me ka ʻenehana hydrolysis bio-enzymatic e hana i nā pauka maʻamau me ka andrographolide content o 8% -98%, e hoʻolaha ana i kāna hoʻomaikaʻi ʻana mai ka lāʻau lapaʻau lāʻau i nā mea waiwai honua.
ʻO nā mea hana koʻikoʻi oAndrographis Paniculata Extractshe mau pūhui lactone diterpenoid, helu no 2% -5%24, ka mea nui me:
- Andrographolide:ʻO ka molecular formula C₂₀H₃₀O₅, helu no 30% -50%, ʻo ia ka mea hana nui no ka antibacterial a me ka anti-inflammatory.
- Dehydroandrographolide:molecular formula C₂₀H₂₈O₄, helu hehee 204 ℃, me ka hana anti-tumor nui.
- 14-Deoxyandrographolide:molecular formula C₂₀H₃₀O₄, me ka maikaʻi maikaʻi loa i ka leptospirosis.
- Neoandrographolide:mole mole C₂₆H₄₀O₈, hiki ke hoʻoheheʻe wai maikaʻi, kūpono no ka hoʻomākaukau waha.
Eia kekahi, flavonoids, phenolic acids a me nā mea ʻaila volatile synergistically hoʻonui i ka hana antioxidant a me ka immunomodulatory.
●He aha nā pōmaikaʻi o Andrographis Paniculata Extract?
1. Immunomodulation A me Anti-Infection
Antibacterial a me antiviral: Loaʻa i ka Andrographolide ka nui o ka inhibition ma luna o 90% ma Staphylococcus aureus a me Shigella dysenteriae, a ua hoʻohālikelike ʻia kona hana lapaʻau i ka mālama ʻana i ka maʻi maʻi bacillary me chloramphenicol. Hiki i kāna ʻāpana wai ke hoʻemi i ka loaʻa ʻana o ka maʻi influenza e 30% a hoʻopōkole i ke ala o ke anu e 50%.
Hoʻonui i ka pale ʻana: Ma ka hoʻoulu ʻana i nā macrophages a me nā lymphocytes T, hiki iā ia ke hoʻonui i ke kiʻekiʻe o nā CD4⁺ lymphocytes i nā maʻi HIV (ʻikepili clinical: 405→501/mm³, p=0.002).
2. Anti-Tumor A me Angiogenesis Inhibition
Kūleʻa anti-tumor: Hiki i ka Dehydroandrographolide ke kāohi i ka ulu ʻana o nā maʻi maʻi W256 i hoʻololi ʻia a keʻakeʻa i ka hoʻonui ʻana o ka maʻi maʻi maʻi ma ke ʻano i hilinaʻi ʻia.
Anti-angiogenesis: Hoʻopili ka Andrographolide i ka angiogenesis tumor ma o ka hoʻohaʻahaʻaʻana i ka'ōlelo VEGFR2 a me ka paleʻana i ke ala hōʻailona ERK / p38, me kahi IC₅₀ o 100-200μM.
3. ʻO ka Metabolism a me ka pale kino
ʻO ka pale ʻana i ka ate a me ka emi ʻana o ka lipid: Mālama ʻo Andrographolide i nā pae glutathione a hōʻemi i ka malondialdehyde (MDA) i loko o ke kumu hoʻohālike o ka hōʻeha ate tetrachloride e 40%, ʻoi aku ka maikaʻi ma mua o ka silymarin.
Ka pale ʻana i ka maʻi maʻi: Hoʻoponopono i ke koena nitric oxide/endothelin, hoʻopaneʻe i ka atherosclerosis, a hoʻemi i nā pae lipid koko i nā rapeti hoʻokolohua.
4. Anti-Inflammatory and Antioxidant
ʻO ka wai wai o ke kumu ka mea ikaika loa e hōʻiliʻili i nā radical manuahi (IC₅₀=4.42μg / mL), ʻo ia ka 4 mau manawa ʻoi aku ka maikaʻi ma mua o nā antioxidants synthetic a kūpono i nā maʻi inflammatory mau loa.
●He aha nā noi oAndrographis Paniculata Extract ?
1. Lapaau a me ka lapaau
Nā lāʻau lapaʻau anti-infective: hoʻohana ʻia no ka maʻi maʻi bacterial, ka maʻi pneumonia a me ka hoʻomākaukau waha no ka pharyngitis, me ka nui o ka lāʻau lapaʻau ma mua o 85%.
ʻO nā lāʻau lapaʻau anti-tumor i hoʻopaʻa ʻia: Ua komo ʻo Andrographolide derivative "Andrographine" i ka Phase II i nā hoʻokolohua lapaʻau no ka maʻi leukemia a me nā ʻōpū paʻa.
ʻO ka mālama ʻana i ka maʻi maʻi maʻi: hoʻomaʻamaʻa kōkua o ka retinopathy diabetic (0.5-2mg/kg/lā) a me ka rheumatoid arthritis (1-3mg/kg/lā).
2. Hanai holoholona a me ka hanau omaomao
ʻO nā lāʻau ʻokoʻa ʻē aʻe: ʻO Compound Andrographis paniculata feed additives e hoʻemi i ka maʻi maʻi o nā puaʻa a hoʻonui i ke ola o nā broilers; e hoʻohui ana i ka 4% extract i ka ʻai carp, hiki i ka 155.1% ka piʻi ʻana o ke kaumaha, a ua hoʻonui ʻia ka helu hoʻololi ʻana i ka 1.11.
Ka pale ʻana a me ka mālama ʻana i ka maʻi: ʻO Andrographis paniculata injection e mālama i ka maʻi maʻi puaʻa a me ka enteritis, me ka nui o ka hoʻōla ʻana o 90% a me ka helu make o 10%.
3. Nā Meaʻai Ola a me nā Kemika o kēlā me kēia lā
Meaʻai hana: Andrographis paniculataunuhiHoʻokuʻu ʻia nā capsules (200mg i kēlā me kēia lā) ma nā mākeke ʻEulopa a me ʻAmelika no ka hoʻoponopono ʻana i ka pale ʻana a me ka pale anu.
Nā huahana mālama ʻili: E hoʻohui i nā mea anti-inflammatory a me nā pale lā e hoʻomaha i ka pōʻino o UV a me ka ʻulaʻula o ka ʻili paʻakikī.
4. Nā Kūlana ma nā kahua e puka mai ana
ʻO nā lāʻau anti-angiogenic: ʻO ka hoʻomohala ʻana i nā hoʻomākaukau i manaʻo ʻia no nā ʻōpū a me ka retinopathy maʻi maʻi i lilo i alakaʻi nui o ka biology synthetic.
ʻO ka mālama ola kino holoholona: Hoʻokuʻu ʻia nā mea hoʻohui anti-inflammatory a immunomodulatory no nā ʻīlio a me nā pōpoki ma ka mākeke ʻAmelika ʻĀkau, me ka ulu ʻana o ka makahiki he 35%.
●Hoolako NU HOUAndrographis Paniculata ExtractPauda
Ka manawa hoʻouna: Jul-18-2025
