● MeneneThiamine hydrochloride ?
Thiamine hydrochloride shine nau'in hydrochloride na bitamin B, tare da tsarin sinadarai C₁₂H₁₇ClN₄OS·HCl, nauyin kwayoyin 337.27, da lambar CAS 67-03-8. Fari ne zuwa launin rawaya-farin crystalline foda mai kamshi mai ɗanɗanon shinkafa da ɗanɗano mai ɗaci. Yana da sauƙi don ɗaukar danshi a cikin busassun yanayi (zai iya sha 4% danshi lokacin da aka fallasa shi zuwa iska). Mahimman kaddarorin jiki da sinadarai sun haɗa da:
Solubility:Mai narkewa sosai a cikin ruwa (1g/mL), dan kadan mai narkewa a cikin ethanol da glycerol, kuma maras narkewa a cikin kaushi na halitta kamar ether da benzene.
Kwanciyar hankali:Barga a cikin yanayin acidic (pH 2-4) kuma yana iya tsayayya da yanayin zafi na 140 ° C; amma yana rushewa da sauri a cikin tsaka-tsaki ko mafita na alkaline kuma ana iya kunna shi cikin sauƙi ta hasken ultraviolet ko wakilai na redox.
Halayen ganowa:Yana amsawa tare da cyanide na ferric don samar da wani abu mai shuɗi mai shuɗi "thiochrome", wanda ya zama tushen ƙididdigar ƙididdiga38.
Tsarin shirye-shirye na duniya na yau da kullun shine haɗin sinadarai, wanda ke amfani da acrylonitrile ko β-ethoxyethyl propionate azaman albarkatun ƙasa kuma ana samarwa ta hanyar haɓakawa, cyclization, sauyawa da sauran matakai, tare da tsafta fiye da 99%.
●Menene Fa'idodinThiamine hydrochloride ?
Thiamine hydrochloride an canza shi zuwa nau'i mai aiki na thiamine pyrophosphate (TPP) a cikin jikin mutum, kuma yana aiki da ayyuka masu yawa:
1. Energy metabolism core:a matsayin coenzyme na α-ketoacid decarboxylase, kai tsaye yana shiga cikin aiwatar da canjin glucose zuwa ATP. Lokacin da ya gaza, yana haifar da tarin pyruvate, yana haifar da lactic acidosis da rikicin makamashi.
2. Kariyar tsarin jijiya:Kula da al'ada tafiyar matakai na jijiya. Rawanci mai tsanani yana haifar da beriberi, tare da alamun bayyanar cututtuka ciki har da neuritis na gefe, atrophy na muscular, da kuma gazawar zuciya. A tarihi, ta haifar da annoba mai yawa a Asiya, inda ta kashe dubban daruruwan mutane a kowace shekara.
3. Ƙimar bincike mai tasowa:
Kariyar ciwon zuciya:Matsakaicin 10μM na iya haifar da lalacewar ƙwayar cuta ta acetaldehyde, hana kunna caspase-3, da rage haɓakar furotin carbonyl.
Anti-neurodegeneration:A cikin gwaje-gwajen dabbobi, rashi na iya haifar da tarawa mara kyau na furotin β-amyloid a cikin kwakwalwa, wanda ke da alaƙa da cututtukan cututtukan Alzheimer.
Ƙungiyoyi masu haɗari don rashi sun haɗa da:cin dogon lokaci na tsayayyen farar shinkafa da gari, masu shan giya (ethanol yana hana shan thiamine), mata masu juna biyu, da marasa lafiya masu fama da zawo.
●Menene Application OfThiamine hydrochloride ?
1. Masana'antar abinci (kaso mafi girma):
Masu haɓaka kayan abinci:an ƙara zuwa samfuran hatsi (3-5mg/kg), abinci na jarirai (4-8mg/kg), da abubuwan sha na madara (1-2mg/kg) don gyara asarar sinadarai masu lalacewa ta hanyar sarrafawa mai kyau.
Kalubalen fasaha:Saboda yana da sauƙin ruɓe a cikin yanayin alkaline, ana amfani da abubuwan da aka samo kamar su thiamine nitrate a matsayin maye gurbin abinci mai gasa.
2. Filin likitanci:
Aikace-aikace na warkewa:Ana amfani da injections don maganin gaggawa na beriberi (nauyin ciwon zuciya / ciwon zuciya), kuma ana amfani da shirye-shiryen baka a matsayin ƙarin jiyya na neuritis da rashin narkewa.
Magungunan haɗin gwiwa:haɗe tare da ma'aikatan magnesium don inganta ingancin Wernicke encephalopathy da rage yawan sake dawowa.
3. Noma da fasahar kere-kere:
Masu haifar da juriya na amfanin gona:50mM maida hankali magani na shinkafa, cucumbers, da dai sauransu, kunna pathogen-related genes (PR genes), da kuma inganta juriya ga fungi da ƙwayoyin cuta.
Abubuwan da ake ciyarwa:Inganta ingancin metabolism na sukari a cikin dabbobi da kaji, musamman a cikin yanayin damuwa na zafi (ƙarin buƙatun fitar gumi).
● SABUWAR KYAUTA mai inganciThiamine hydrochlorideFoda
Lokacin aikawa: Juni-30-2025
