● Meneneβ-NAD ?
β-Nicotinamide Adenine Dinucleotide (β-NAD) shine mabuɗin coenzyme da ke cikin dukkan sel masu rai, tare da tsarin kwayoyin halitta na C₂₁H₂₇N₇O₁₄P₂, da nauyin kwayoyin 663.43. A matsayin babban mai ɗaukar halayen redox, ƙaddamarwarsa kai tsaye yana ƙayyade ingancin makamashin salula kuma an san shi da "kuɗin makamashin salula".
Halayen rarraba dabi'a:
Bambance-bambancen nama: Abubuwan da ke cikin sel myocardial shine mafi girma (kimanin 0.3-0.5 mM), sannan hanta, kuma mafi ƙasƙanci a cikin fata (raguwa da 50% kowace shekara 20 tare da shekaru);
Siffar wanzuwa: gami da nau'in oxidized (NAD⁺) da sigar rage (NADH), da ma'auni mai ƙarfi na ma'auni tsakanin su biyun yana nuna yanayin metabolism na salula.
● Kariyar Radiation naβ-NAD.
Haɓaka adadin tsirar ƙwayoyin sel na hematopoietic bayan bayyanar radiation da sau 3, da karɓar kulawa mai mahimmanci daga aikin lafiyar sararin samaniya na NASA.
Tushen shiri: Daga hakar ilmin halitta zuwa juyin halitta na roba
1. Hanyar hakar gargajiya
Raw kayan: Kwayoyin yisti (abun ciki 0.1% -0.3%), hanta dabba;
Tsari: ultrasonic crushing → ion musayar chromatography → daskare bushewa,β-NADtsarki ≥ 95%.
2. Enzyme catalytic kira (tsari na yau da kullun)
Substrate: Nicotinamide + 5'-phosphoribosyl pyrophosphate (PRPP);
Amfani: Fasahar enzyme mara motsi na iya ƙara yawan amfanin β-NAD zuwa 97%.
3. Halittar halitta ta roba (alkiblar gaba)
Escherichia coli da aka gyara:Wani nau'in injiniyan injiniya wanda ChromaDex, Amurka ya gina, tare da yawan amfanin fermentation na 6 g/L;
Al'adar ƙwayoyin shuka: Tsarin tushen gashi na taba yana fahimtar yawan samar da NAD precursor NR.
● Menene fa'idodinβ-NAD?
1. Anti-tsufa core inji
Kunna Sirtuins:Ƙara SIRT1/3 ayyuka ta sau 3-5, gyara lalacewar DNA, da ƙara tsawon rayuwar yisti da 31%;
Ƙarfafawa Mitochondrial:Nazarin asibiti ya nuna cewa mutanen da ke da shekaru 50-70 sun ƙara 500 MG NMN kowace rana, kuma samar da ATP tsoka yana ƙaruwa da 25% bayan makonni 6.
2. Neuroprotection
Cutar Alzheimer:Mayar da matakan NAD⁺ na neuronal na iya rage β-amyloid deposition, kuma aikin fahimi na ƙirar linzamin kwamfuta yana inganta ta 40%;
Cutar Parkinson: β-NADKare ƙwayoyin cuta na dopaminergic ta hanyar hanawa PARP1.
3. Cutar da ke fama da cutar siga
Ciwon sukari:Haɓaka hankalin insulin, gwaje-gwajen linzamin kwamfuta masu kiba sun nuna raguwar 30% a cikin sukarin jini;
Kariyar zuciya:Inganta aikin endothelial, da kuma rage yankin atherosclerotic plaques da 50%.
● Menene Aikace-aikace Naβ-NAD?
1. Filin likitanci
Magungunan rigakafin tsufa: Shirye-shiryen NMN da yawa sun sami takaddun shaida azaman magungunan marayu ta FDA don mitochondrial myopathy;
Cututtukan Neurodegenerative: NAD⁺ allurar cikin jijiya ta shiga gwajin asibiti na Phase II (alamomi ga cutar Alzheimer).
2. Abinci masu aiki
Kariyar baka: β-NADkamar yadda NAD precursor (NR/NMN) capsules suna da tallace-tallace na shekara-shekara fiye da dala miliyan 500.
Abincin wasanni:Haɓaka juriyar 'yan wasa, kuma akwai wasu masu inganta NAD akan kasuwa don haɓaka ayyukan wasanni.
3. Na'urar kwaskwarima
Asalin hana tsufa:0.1% -1% NAD⁺ hadaddun, an gwada don rage zurfin wrinkle da 37%;
Kula da kai:Kunna sel mai tushe na gashi, kuma ƙara masu haɓaka NAD zuwa shamfu na hana asarar gashi.
4. Noma da binciken kimiyya
Lafiyar dabbobi:Ƙara abubuwan NAD don shuka abinci yana ƙara adadin alade da 15%;
Gano Halittu:Ana amfani da rabon NAD/NADH azaman alamar yanayin rayuwa ta sel don gwajin cutar kansa na farko.
●NEWGREEN Supplyβ-NADFoda
Lokacin aikawa: Juni-17-2025
